Abstract
In the present work isoniazid, pyrazinamide, fluconazole, metformin and losartan potassium were chosen and transformed into complexes upon their interaction with metal salts. Physico-chemical properties of the resultant complexes and antibacterial activity against 5 gram positive and 2 gram negative species are determined. Some of our newly synthesized complexes demonstrated higher activity as compared to their respective ligand.

Ghazala Ishrat, Mansoor Ahmed, Mohsin Ali, Samina Perveen, Seyed Abdulmajid Ayatollahi, Syed Moazzam Haider, Shakil Ahmed. (2020) METAL ION-DRUG INTERACTION: PHYSICO-CHEMICAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF METAL COMPLEXES DERIVED FROM ESTABLISHED DRUGS, , Volume 17, Issue 2.
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