Abstract
Grand multiparity is always a risk in pregnancy and is tied to a high prevalence of maternal and neonatal health issues compared with other multiparous. The study was performed to compare the concentrations of cardiac function lab tests in grand multiparas with nulliparas [control] and primiparas. A cross-sectional study was performed in 100 nonpregnant women as control group, 100 primiparity pregnant women, and 100 grand multiparity pregnant women. All pregnant women were between 20th - 30th weeks of gestation. High-sensitivity C – reactive protein [us-CRP], total homocysteine [Hyc] and creatine kinase-MB [CK-MB], total cholesterol [T.CHOL], as well as high density lipoprotein cholesterol [HDL-C] and Cholesterol/HDL ratio were measured. Multiparity pregnant ladies showed significant raise throughout the total blood cholesterol, CHOL/HDL ratio in addition to High-sensitivity C - reactive protein levels when compared to control and primiparity. On the other hand, high density lipoprotein-cholesterol and creatine kinase-MB of multiparity group increased significantly when compared to control group, but showed significant decrease as compared to primiparity. Homocysteine levels in multiparity group were increased significantly when compared to control group. The results suggest that grand multiparity increases the risk of pregnancy-related complication secondary to cardiac dysfunction.
