Abstract
Most of the studies consider the significance of creatine kinase (CK) and myoglobin (Mb) as the best markers of skeletal muscle injury after high force eccentric exercise (ECE). To confirm this and the activity of other injury markers mainly lactate dehydrogenase (LDH), C-reactive protein (CRP), aldolase, fatty acid binding protein (FABP) and aspartate aminotransferase (AST), eighteen physically active and healthy male Saudis (mean age: 22.5 years (range: 18-27 years); basal body weight: 70 kg (range: 58-78 kg) from Makkah (Saudi Arabia) were included in the ECE program using cycle ergometer. Highly significant post-ECE increase compared to pre-ECE in CK, Mb, LDH, FABP, CRP and AST were recorded whereas no significant variation occurred in aldolase activity.