Abstract
Nine Penicillium species were isolated from different sources and were screened for antibacterial potential against ten common
bacterial strains. Bacillus sp. (FCBP 234) and Acetobacter xylinum (FCBP 239) was the most sensitive to culture filtrates of P.
granulatum (FCBP 1080), P. verrucosum var. cyclopium (FCBP 1052), P. billii (FCBP 1079) and P. expansum (FCBP 1102), with
maximum inhibition zone diameters of 4.2 and 4.0 cm, respectively. On the other hand, filtrates of P. simplicissimum (FCBP 022),
P. citrinum (FCBP 024), P. oxalicum (FCBP 025) and Penicillium sp. (FCBP 1069) were weak to least effective to control the growth
of all tested bacteria. The preliminary data led us to conclude that, test Penicillium strains have remarkable antibacterial potential.
These locally isolated Penicillium strains can be used for novel fungal natural products in biotechnological applications.
