Hyperlipidemia is one of the major contributors to atherosclerosis and coronary heart disease. Non-pharmacological dietary therapy and exercise are the first line of treatment in Hyperlipidemia and several dietary components with such effects have been known. The present study has been undertaken to investigate the antiatherogenic effect of fresh grated ginger (Zingiber Officinale) in cholesterol fed rabbits with relation to its antihyperlipidemic activity. The mark rise in serum cholesterol, triglyceride and LDL-C in cholesterol fed rabbits was significantly reduced by the administration of fresh ginger (p