Abstract
In this study, biological activity of some fractions for Achillea biebersteinii and A.millefolium (Compositae) was evaluated in vitro
against the epimastigotes of Trypanosoma cruzi, the parasitic agent of Chagas disease. Diethyl ether fractions of both plants were the
most active fraction (MLC= 12.5 μMl). The trypanocidal activity seems to be decrease by fractionation using MeOH and water as
solvents. The results obtained from biological assay revealed that Achillea could be a source of active trypanocidal compounds. In
addition, the preliminary phytochemical studies showed that the active fractions were rich of terpenoids and flavonoids.
