Abstract
Purpose: To compare the central macular thickness amongst diabetics with that
of healthy population by using Optical Coherence Tomography.
Study Design: Case control study.
Place and Duration of Study: Department of Ophthalmology Unit I, Civil
Hospital Karachi from 5th March 2012 to 4th September 2012.
Material and Methods: We randomly selected patients with diabetes (cases)
and healthy patients (control) with clinically normal macula and no diabetic
retinopathy. Detailed relevant history was acquired. Best corrected visual acuity
(BCVA) was measured with standard Snellen’s chart. Detailed dilated fundus
examination was done using +90D and +78D lens. Central macular thickness
within an area of 1000 µm was measured using Optical Coherence Tomography.
Results: There were 68 patients in each group. The mean age of patients in the
Diabetic group was 47.94 ± 14 (20-80) years and in the healthy group it was
found to be 39.53 ± 14.93 (20-80) years. Out of these 26 were male and 42 were
female in the diabetic group whereas 27 were male and 41 were female in the
healthy group. Mean central macular thickness of Diabetic eyes were 214.48 ±
31.41 µm and that of healthy eyes were 236.79 ± 19.38 µm with mean difference
of 22.31 ± 4 µm (p value = 0.000).. A statistically significant difference in the
central macular thickness of Diabetics and healthy patients was observed.
Conclusion: The central macular thickness is significantly decreased in eyes of
patients with Diabetes.
Beenish Khan, Muhammad Muneer Quraishy, Asma Shams. (2019) Central Macular Thickness: A Comparative Study of Diabetics Vs Healthy, Pakistan Journal of Ophthalmology, Volume 35, Issue 1.
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