Abstract
Out of thirty-eight healthy rabbits acclimatized to the optimal laboratory conditions, six were kept as normal control and rest were inoculated intraperitoneally and subcutaneously with 45,000 protoscoleces of Echinococcus granulosus of sheep origin. They were randomly divided into four groups i.e., one infected control (n=8) and three treated groups (having 8 rabbits in each group). These treated rabbits were individually given (2g/day) leaves of Aloe vera or ovary part of Punica granatum or fruit of Azadirachia indica along with ordinary green fodder. Rabbits were individually weighed and their blood samples were pooled for haematological analyses up to 90 days with an interval of 10 days. The body weight (g) in the experimental control rabbits decreased (<0.001) and in treated rabbits body weight initially decreased but later on improved gradually (P <40.001). Among ,haematological parameters total erythrocyte counts (TEC) (10 mm"), haemoglobo (g/d1), packed cell volume (% nil); total leukocyte counts (TLC) (thousands/mm ), and erythrocyte sedimentation rate (mm/hr) fluctuated in the rabbits inoculated with protoscoleces of sheep origin. However, these values improved gradually in the rabbits treated with different plants/parts of plants. The improvement was significant in the rabbits treated with leaves of A. vera and fruit of A. indica as compared to those given ovary part of P. granatum. Their respective haematological indices i.e., mean corpuscular volume (femtolitre), mean corpuscular haemoglobin (picogram) and mean corpuscular haemoglobin concentration (g/dl) also reflected the changes faced by haemoglobin and packed cell volume. The above results showed that all the three plants play important role in curing the haematological parameter in experimentally induced hydatidosis. These plants may have some chemical that can antagonise the effects of protoscoleces.
AKHTAR TANVEER . (1999) CONTROL OF HYDATIDOSIS THROUGH LOCAL PLANTS: HAEMATOLOGICAL STUDIES , Punjab University Journal of Zoology, Volume 14, Issue 1.
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