Abstract
Out of twenty-six healthy rabbits acclimatized to the optimal laboratory conditions for fifteen days, 4 were considered as normal control and twenty-two were inoculated (intraperitoneally and subcutaneously) with 45000 protoscoleces of Echinococcus granulosus of sheep origin. They were at random divided into 4 groups. Groups 1-3 were orally given (2g/day) mashed leaves of Aloe vera, powdered Punica granatum (unripped ovary part) and fruit of Azadirachta indica respectively. Group 4 was considered as infected control. All the rabbits were fed on seasonal green fodder and ordinary tap water ad libitum. Their blood samples were pooled after every 10 days upto 70 days for biochemical analyses. Increased (P< 0.001) body weight was noted in experimental rabbits. It was clear from the biochemical results that activities of acid phosphatase, alkaline phosphatase and glucose decreased (P<0.001) in rabbits treated with A. vera, P. granatum and A. indica as compared to normal control and the values of glutamic oxaloacetic transaminase, glutamicpyruvic transaminase, cholesterol and total protein improved (P<0.001) as a result of herbal treatment. The bilirubin value improved only in rabbits treated with A. vera and A. indica (P<0.001). The results of our present investigation showed that alterations in different enzymes and biochemical metabolites induced by liver protoscoleces were improved in the rabbits orally given A. vera, P. granatum and A. indica. Although the extent of improvement varies in these plants, even then the present results are promising and it is suggested that the active ingredients of these plants should be checked for further use.
AKHTAR TANVEER, RIFFAT MUSTAFA, ZAHEER ANWAR . (1998) CONTROL OF HYDATIDOSIS IN RABBITS THROUGH FEEDING LOCAL PLANTS , Punjab University Journal of Zoology, Volume 13, Issue 1.
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