Abstract
Coronary artery disease (CAD) is the leading cause of death in the Indo-Pakistan subcontinent aswell as globally.Coronary angiography is considered thegold standard test for the diagnosis of CAD. Therefore, an accurate interpretation of coronary angiography is of paramount importancein decision-making to treat patients with CAD.Coronary angiography has the inherent limitation of being a two-dimensionalX-Ray lumenogram of a complex three-dimensional vascular structure. Visual assessment of angiogram can lead to both inter-and intra-observer variability inthe assessment of the severity and extent of the disease which can lead to differencesin management strategies. This issuebecomeseven more relevantwhen assessing left main stem(LMS), bifurcations, diffusecoronary artery diseaseorsituations involving complex coronary morphology. Interventional cardiology has been revolutionised by recent advances in techniques, and innovative technologies in the catheterisation laboratory. Today, a modern catheterisation laboratory is equipped with adjunctive technologies, such as Quantitative Coronary Angiography (QCA),Fractional Flow Reserve (FFR), Intra-Vascular Ultra-Sonography (IVUS), and Optical Coherence Tomography (OCT), to help cliniciansmake a well-informed decision based on detailed anatomicaland physiological assessment of a coronary artery rather than judgement based solely on visual assessment. In this article, we have briefly described the utility and evidence behind these adjunctive modalities and have provided examples ofclinical cases to highlight their use in aiding physiciansto make a well-informed treatment decision

Yasir Parviz,, Sethumadhavan Vijayan, Ayyaz Sultan, Javaid Iqbal. (2017) ROLE OF INTRA CORONARY IMAGING AND PHYSIOLOGY IN DIAGNOSIS AND MANAGEMENT OF CORONARY ARTERY DISEASE, JOURNAL OF AYUB MEDICAL COLLEGE ABBOTTABAD, Volume 29, Issue 3.
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