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Objective: To determine the association of pre-eclampsia in pregnant women in the early second trimester diagnosed with hypertriglyceridemia.
Methodology: This descriptive case series study was conducted in Unit II, Department of Obstetrics and Gynecology, Fauji Faundation Hospital, Rawalpindi from 21st March 2017 to 20th September 2017. Seventy-five women of 18-35 years old age in their early second trimester (14-20 weeks) having singleton pregnancy with hypertriglyceridemia (triglyceride level >150mg/dl) were included for this study. At each visit of the patient, her blood pressure was checked. In case, she had hypertension (BP >140/90mmHg), tests were done for detection of proteins in urine either with dipstick method or by urine R/E. All the required information was recorded in predesigned proforma. Follow-up continued till delivery.
Results: Pre-eclampsia was developed in 17 patients out of a total of 75 (22.7%). Stratification was also carried out with regards to the factors (age of the patient, gestational age, and Body Mass Index (BMI)). However, the results showed that there was no association of the above-mentioned factors with the development of pre-eclampsia.
Conclusion: The study results showed that there is an association between hypertriglyceridemia in the early second trimester of pregnancy and the subsequent development of preeclampsia. However, further studies are needed to determine the relationship between maternal hypertriglyceridemia and the risk of developing pre-eclampsia.
Aisha Jalil, Zartaj Hayat. (2020) Association of Serum Lipid Profile in Early 2nd Trimester in Pregnant Patients with Pre Eclampsia, Journal of the Society of Obstetrics and Gynaecologists of Pakistan , Volume-10, Issue-4.
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