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This report aimed to document the genomic characterization and the genetic profile analysis related to the
dissemination of beta-lactams and vancomycin through Mobile Genetic Elements (plasmids, insertion sequences and
transposons) in different settings including clinical and sewage water. PubMed and Medline database were used to
search the relevant literature from 2004 to 2020 and data of interest from Central for Diseases Control and Prevention
and those predicted by the WHO were also included. Genetic profile analysis showed diversity of Mobile Genetic
Elements (MGEs) with the predominance of conjugative IncF plasmids types and insertion sequences elements
carrying cephalosporins, carbapenem and vancomycin resistance genes. The propagation of these genetic elements
constitutes a veritable global health threat and urges to establish new strategic plan for combating antibiotic resistance
in Saudi Arabia.
Sihem Mahrouki. (2021) DISSEMINATION OF CONJUGATIVE INCF PLASMIDS AND INSERTION SEQUENCES ELEMENTS ASSOCIATED WITH ANTIMICROBIAL RESISTANCE IN SAUDI ARABIA: A SERIOUS HEALTH THREAT , , Volume 18, Issue 4.
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