Abstract
From time immemorial man has been interested in trying to control disease. It is true that medicine was conceived in sympathy and born out of necessity. The first doctor was the first man and the first women the first nurse. Primitive medicine is timeless. Primitive medicine still persists in many parts of the world if we look around the world. Today the world stands on the threshold of a new era in which hundreds of millions of people will be safe from some of the most terrible diseases.1 Soon poliomyelitis neonatal tetanus, measles, leprosy will join smallpox as diseases of the past. On the other hand the world also stands on the brink of global crises in infectious diseases. No country is safe from them and no country can afford to ignore their threat any longer. Some infectious diseases once thought to be conquered have returned with revenge. Remaining others has developed obdurate resistance to antimicrobial drugs. Previously unknown and new diseases continue to emerge making crisis for today and challenge for future. Antimicrobial are the most important life saving drugs used to cure microbial diseases. The first antimicrobial discovered was penicillin, which was discovered accidentally in 1940s. More than hundred 100 different antibiotics are available to treat small illnesses as well as fulminating and life threatening infections. Frequent use of antibiotics in inappropriate dosage for long duration causes resistance to antimicrobials. Ability of microbes to grow in the presence of a chemical (drug) that would normally kill them or limit their growth is called Antimicrobial resistance. The antimicrobial resistance makes it difficult to eliminate infections from the body as the drugs become ineffective or less effective. According to WHO Antimicrobial resistance is ineffectiveness to antimicrobial agents in standard doses is called Antimicrobial resistance. A phenomenon which is natural biological and unstoppable is driven by unchecked and misuse of antimicrobial agents.
Muhammad Ayaz Bhatti, Abdul Bari Khan . (2014) Increasing Antimicrobial Resistance "A Crisis for Today and Challenge for Future", Journal of Islamic International Medical College, Volume-9, Issue-2.
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