Abstract
Present study was performed to evaluate the Phytochemistry, antioxidant, antifungal and cytotoxic potential of Tephrosia purpurea methanolic extract. The plant of Tephrosia purpurea was purchased from a herbal shop at local market of district Bannu, dried, grounded to powder form and was then saturated with methanol to prepare methanolic crude extract. The phytochemical screening of Tephrosia purpurea showed the presence of saponins, phlobatannins, tannins and terpenoids while anthraquinones and flavonoids are absent. The plant showed 90% death rate of brine shrimps after 24 hrs and 100% after 48 hrs at 3mg/mL concentration. It also showed inhibition against fungus Aspergillus flavus, Aspergillus niger and Aspergillus fumigatus which are 89, 90 and 91% respectively at 3mg/mL concentration. Free radical scavenging activity of Tephrosia purpurea at 3mg/mL concentration was also very significant which are 89, 90, 8%, 74, 78 and 85% against DPPH, Phosphomolybdate, Hydroxyl radicals, Hydrogen peroxide, ABTS and Beta carotene, respectively.
