Abstract
Osteoarthritis is a chronic escalating degenerative joint disorder characterized by mechanical malformations affecting degradation of joints, including articular cartilage and subchondral bone. Exercise is related with oxidative stress and tissue breakdown therefore, the aim of this article is a presentation of current knowledge of the modification in the amount of antioxidant vitamins. The total antioxidant capacity was also observed as a result of exercise in patients with knee osteoarthritis. Fifteen patients with knee osteoarthritis were enrolled in the study. One of the groups remained untreated and was called Group “A”, was considered as control. Group “B” was the experimental group treated with Exercises only. Total antioxidant capacity (TAC) and antioxidants Vitamins (Vitamin C and Vitamin E) levels in plasma were determined before and after, following three months of exercise. It was observed that exercise had no effect on total antioxidant capacity, Vitamin C, and Vitamin E, levels in plasma. The total antioxidant capacity levels, increase up to 4.37% when exercise is given to the osteoarthritis patients. Whereas Vitamin E concentration increased by 10.91% and Vitamin C content by 4.72% when given to the osteoarthritis patients. These level of total antioxidant capacity and Vitamin C remained statistically non significant, but Vitamin E concentration shows significant improvement. The result of our study suggested that exercises did not affect the serum total antioxidant capacity, Vitamin C, levels when given to the osteoarthritis patients and Vitamin E level slightly increase, and it might be due to the frequency, intensity, and duration of the exercise or the gender and the variation in the severity of symptoms.
