Abstract
Staphylococcus aureus and Coagulase Negative Staphylococci (CoNS) are significant pathogens of humans and emergence of multidrug resistant (MDR) strains is limiting the treatment options against these organisms. The resistance pattern of 60 strains of staphylococci isolated from different clinical specimens was determined using the disc diffusion method. Of the 60 staphylococcus isolates, 43 were identified as S. aureus and 17 were CoNS. In the present study, 98% (442/43) of S. aureus isolates were resistant to amoxicillin, 88% (38/43) to gentamicin, 81% (35/43) to penicillin and 67% (29/43) to tetracycline. This study showed a high rate of methicillin resistance among S. aureus (37%) and CoNS (59%). Emergence of vancomycin resistance was observed not only in S. aureus (1/43) but also in CoNS (2/17). The study also revealed prevalence of multidrug resistance among both S. aureus (86%) and CoNS (82%) isolates. Only one isolate of CoNS was susceptible to all the six antibiotics used in this study.
